SHLD1

Across TCGA patient cohorts, SHLD1 mutation is significantly associated with the total protein of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SHLD1-associated genes across cancer lineages are Myosin-IIa. Each is linked with SHLD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SHLD1-to-partner and partner-to-SHLD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Myosin-IIa grouped by SHLD1-low versus SHLD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SHLD1→partner) and Y-score (partner→SHLD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Myosin-IIa →	+0.233	+2.814	.040	.036	1	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Myosin-IIa by SHLD1 expression — UCEC

Explore this box plot interactively →