SHISAL2B

Across TCGA cell cohorts, SHISAL2B RNA expression is significantly associated with the go_rna of many other GO terms, with 927 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible SHISAL2B-associated GO terms across cancer lineages are Regulation of syncytium formation by plasma membrane fusion, tRNA transcription by RNA polymerase III, and Engulfment of apoptotic cell. Each is linked with SHISAL2B in more than 4 cancer types. Because this analysis shows association rather than direction, both SHISAL2B-to-partner and partner-to-SHISAL2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of syncytium formation by plasma membrane fusion grouped by SHISAL2B-low versus SHISAL2B-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SHISAL2B→partner) and Y-score (partner→SHISAL2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of syncytium formation by plasma membrane fusion →	+0.083	+1.293	.002	.006	3	5
LUNG_NSCLC_LUAD	tRNA transcription by RNA polymerase III →	+0.045	+0.133	.002	.007	3	5
SOFT_TISSUE	Engulfment of apoptotic cell →	-0.187	-2.091	<.001	<.001	3	4
LUNG_SCLC	Regulation of TORC1 signaling →	+0.045	+1.309	<.001	<.001	3	4
LUNG_SCLC	Ribonucleoside triphosphate biosynthetic process →	+0.100	+1.527	<.001	<.001	3	4
SOFT_TISSUE	Muscle organ development →	-0.102	-1.848	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 927 associations by consensus.

Regulation of syncytium formation by plasma membrane fusion by SHISAL2B expression — LUNG_SCLC

Explore this box plot interactively →