SHISAL2A

Across TCGA cell cohorts, SHISAL2A RNA expression is significantly associated with the go_rna of many other GO terms, with 1,603 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SHISAL2A-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Regulation of myoblast fusion, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with SHISAL2A in more than 8 cancer types. Because this analysis shows association rather than direction, both SHISAL2A-to-partner and partner-to-SHISAL2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by SHISAL2A-low versus SHISAL2A-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SHISAL2A→partner) and Y-score (partner→SHISAL2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Negative regulation of myoblast fusion →	+0.099	+0.113	<.001	.008	3	9
BREAST	Regulation of myoblast fusion →	+0.086	+0.113	<.001	.008	2	9
BREAST	Negative regulation of syncytium formation by plasma membrane fusion →	+0.101	+0.113	<.001	.008	3	8
LUNG_SCLC	Regulation of syncytium formation by plasma membrane fusion →	+0.083	+0.604	.003	.004	3	7
OVARY	Spermatid development →	-0.030	-0.129	.001	.002	3	7
OVARY	Cytoplasmic translation →	+0.067	+0.131	.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,603 associations by consensus.

Negative regulation of myoblast fusion by SHISAL2A expression — BREAST

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