SHISAL1

Across TCGA cell cohorts, SHISAL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,190 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SHISAL1-associated GO terms across cancer lineages are Positive regulation of cytoskeleton organization, Regulation of cell-substrate junction assembly, and Collagen metabolic process. Each is linked with SHISAL1 in more than 10 cancer types. Because this analysis shows association rather than direction, both SHISAL1-to-partner and partner-to-SHISAL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cytoskeleton organization grouped by SHISAL1-low versus SHISAL1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SHISAL1→partner) and Y-score (partner→SHISAL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Positive regulation of cytoskeleton organization →	+0.057	+1.696	<.001	.003	3	11
BONE	Regulation of cell-substrate junction assembly →	+0.128	+1.836	.005	.004	3	10
BONE	Collagen metabolic process →	+0.181	+1.822	.006	.003	3	10
BONE	Regulation of focal adhesion assembly →	+0.128	+1.836	.005	.004	3	10
BREAST	Positive regulation of focal adhesion assembly →	+0.118	+1.087	<.001	<.001	3	10
LIVER	Negative regulation of organelle assembly →	+0.064	+1.046	<.001	.006	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,190 associations by consensus.

Positive regulation of cytoskeleton organization by SHISAL1 expression — BREAST

Explore this box plot interactively →