Across TCGA patient cohorts, SHISA7 mutation is significantly associated with the RNA expression of many other genes, with 2,595 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SHISA7-associated genes across cancer lineages are RNU7-176P, PLCE1P1, and BTBD10. Each is linked with SHISA7 in more than 1 cancer types. Because this analysis shows association rather than direction, both SHISA7-to-partner and partner-to-SHISA7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SHISA7→partner) and Y-score (partner→SHISA7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU7-176P →	+0.537	+7.741	<.001	.009	3	2
BRCA	PLCE1P1 →	+0.118	+7.731	<.001	.009	3	1
UCEC	BTBD10 →	+0.589	+2.627	<.001	<.001	3	1
UCEC	LIN7C →	+0.632	+2.606	<.001	<.001	3	1
UCEC	IMMP1L →	+0.399	+2.839	.003	.001	3	1
UCEC	HSD17B12 →	+0.550	+2.584	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,595 associations by consensus.

Exploration

SHISA7 survival (RNA) · tumor vs normal (RNA) · all SHISA7 data types