Across TCGA cell cohorts, SHISA7 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,253 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SHISA7-associated GO terms across cancer lineages are Regulation of transcription initiation by RNA polymerase II, Regulation of blood pressure, and Positive regulation of DNA repair. Each is linked with SHISA7 in more than 10 cancer types. Because this analysis shows association rather than direction, both SHISA7-to-partner and partner-to-SHISA7 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SHISA7→partner) and Y-score (partner→SHISA7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of transcription initiation by RNA polymerase II →	+0.049	+0.058	<.001	.005	3	11
BONE	Regulation of blood pressure →	-0.141	-1.442	<.001	.004	3	8
BONE	Positive regulation of DNA repair →	+0.079	+1.550	<.001	<.001	3	8
BLOOD_Lymphoma	Positive regulation of DNA metabolic process →	+0.046	+0.077	<.001	.001	3	8
SOFT_TISSUE	Regulation of double-strand break repair →	+0.085	+0.184	<.001	<.001	3	8
LUNG_SCLC	Regulation of nucleotide-excision repair →	+0.125	+1.824	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,253 associations by consensus.

Exploration

SHISA7 survival (RNA) · tumor vs normal (RNA) · all SHISA7 data types