Across TCGA cell cohorts, SHISA7 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SHISA7-associated genes across cancer lineages are GHRHR, MAGEB5, and GTSF1L. Each is linked with SHISA7 in more than 1 cancer types. Because this analysis shows association rather than direction, both SHISA7-to-partner and partner-to-SHISA7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SHISA7→partner) and Y-score (partner→SHISA7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	GHRHR →	+0.176	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUSC	MAGEB5 →	+0.033	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUAD	GTSF1L →	+0.045	+3.544	<.001	.009	3	1
LUNG_NSCLC_LUAD	SSX7 →	+0.013	+4.078	<.001	.009	3	1
SKIN	TCP10L2 →	+0.104	+4.415	<.001	.007	3	1
SKIN	CETN1 →	+0.010	+5.022	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Exploration

SHISA7 survival (RNA) · tumor vs normal (RNA) · all SHISA7 data types