Across TCGA cell cohorts, SHISA4 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,981 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SHISA4-associated GO terms across cancer lineages are Golgi vesicle transport, Process utilizing autophagic mechanism, and Autophagy. Each is linked with SHISA4 in more than 16 cancer types. Because this analysis shows association rather than direction, both SHISA4-to-partner and partner-to-SHISA4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SHISA4→partner) and Y-score (partner→SHISA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Golgi vesicle transport →	+0.086	+2.266	.001	<.001	3	17
BONE	Process utilizing autophagic mechanism →	+0.083	+1.863	<.001	.001	3	16
BONE	Autophagy →	+0.083	+1.863	<.001	.001	3	16
BONE	Macroautophagy →	+0.076	+1.876	<.001	.001	3	16
BREAST	Cell division →	+0.088	+2.064	<.001	<.001	3	15
SOFT_TISSUE	Protein folding →	+0.068	+1.775	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,981 associations by consensus.

Exploration

SHISA4 survival (RNA) · tumor vs normal (RNA) · all SHISA4 data types