SHISA3

Across TCGA patient cohorts, SHISA3 RNA expression is significantly associated with the RNA expression of many other genes, with 12,889 significant associations in total. ESCA shows the largest number of these associations.

The most reproducible SHISA3-associated genes across cancer lineages are COL14A1, ZFPM2, and MGP. Each is linked with SHISA3 in more than 24 cancer types. Because this analysis shows association rather than direction, both SHISA3-to-partner and partner-to-SHISA3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SHISA3 versus COL14A1 in CHOL, with a Pearson correlation of 0.76.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SHISA3→partner) and Y-score (partner→SHISA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CHOL	COL14A1 →	+2.019	+1.311	<.001	<.001	3	25
CHOL	ZFPM2 →	+1.288	+2.199	<.001	<.001	3	25
STAD	MGP →	+2.229	+1.874	<.001	<.001	3	23
PAAD	CHRDL1 →	+2.374	+1.070	<.001	<.001	3	23
SARC	NAP1L3 →	+1.200	+1.598	<.001	<.001	3	22
STAD	FAT4 →	+1.072	+1.745	<.001	<.001	3	22

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,889 associations by consensus.

SHISA3 vs COL14A1 — CHOL

Explore this scatter interactively →