SHE

Across TCGA cell cohorts, SHE RNA expression is significantly associated with the go_rna of many other GO terms, with 634 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SHE-associated GO terms across cancer lineages are Axoneme assembly, Regulation of cardiac muscle cell membrane repolarization, and Microtubule bundle formation. Each is linked with SHE in more than 6 cancer types. Because this analysis shows association rather than direction, both SHE-to-partner and partner-to-SHE results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Axoneme assembly grouped by SHE-low versus SHE-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SHE→partner) and Y-score (partner→SHE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Axoneme assembly →	-0.039	-0.035	<.001	.003	3	7
SKIN	Regulation of cardiac muscle cell membrane repolarization →	-0.062	-0.294	<.001	.006	3	6
OVARY	Microtubule bundle formation →	-0.028	-0.328	<.001	.005	3	5
BONE	RNA polymerase II preinitiation complex assembly →	+0.066	+0.301	.003	.009	3	5
BLOOD_Leukemia	Antibacterial humoral response →	+0.069	+0.160	.009	.009	3	4
BLOOD_Leukemia	Glycoprotein catabolic process →	+0.071	+0.194	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 634 associations by consensus.

Axoneme assembly by SHE expression — URINARY_TRACT

Explore this box plot interactively →