SHCBP1

Across TCGA patient cohorts, SHCBP1 protein abundance is significantly associated with the RNA expression of many other genes, with 7,635 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SHCBP1-associated genes across cancer lineages are PLK1, CCNB1, and CEP55. Each is linked with SHCBP1 in more than 6 cancer types. Because this analysis shows association rather than direction, both SHCBP1-to-partner and partner-to-SHCBP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SHCBP1 versus PLK1 in UCEC, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SHCBP1→partner) and Y-score (partner→SHCBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PLK1 →	+0.970	+0.678	<.001	<.001	3	7
UCEC	CCNB1 →	+1.556	+0.761	<.001	<.001	3	6
UCEC	CEP55 →	+1.081	+0.499	<.001	<.001	3	6
UCEC	TUBA1C →	+0.967	+0.676	<.001	<.001	3	6
BRCA	RRM2 →	+1.356	+0.664	<.001	<.001	3	6
UCEC	KPNA2 →	+1.081	+0.760	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,635 associations by consensus.

SHCBP1 vs PLK1 — UCEC

Explore this scatter interactively →