SHCBP1

Across TCGA cell cohorts, SHCBP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,819 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SHCBP1-associated GO terms across cancer lineages are Nuclear chromosome segregation, Chromosome segregation, and Regulation of mitotic nuclear division. Each is linked with SHCBP1 in more than 17 cancer types. Because this analysis shows association rather than direction, both SHCBP1-to-partner and partner-to-SHCBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear chromosome segregation grouped by SHCBP1-low versus SHCBP1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SHCBP1→partner) and Y-score (partner→SHCBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Nuclear chromosome segregation →	+0.178	+1.681	<.001	<.001	3	18
OESOPHAGUS	Chromosome segregation →	+0.170	+1.899	<.001	<.001	3	18
OESOPHAGUS	Regulation of mitotic nuclear division →	+0.155	+1.722	<.001	<.001	3	18
OESOPHAGUS	Regulation of mitotic sister chromatid separation →	+0.217	+1.456	<.001	.003	3	18
OESOPHAGUS	Mitotic nuclear division →	+0.174	+1.742	<.001	<.001	3	18
OESOPHAGUS	Regulation of chromosome separation →	+0.222	+1.661	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,819 associations by consensus.

Nuclear chromosome segregation by SHCBP1 expression — OESOPHAGUS

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