SHC1P1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SHC1P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,247 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SHC1P1-associated GO terms across cancer lineages are Endoplasmic reticulum to Golgi vesicle-mediated transport, rRNA modification, and Positive regulation of intracellular transport. Each is linked with SHC1P1 in more than 11 cancer types. Because this analysis shows association rather than direction, both SHC1P1-to-partner and partner-to-SHC1P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endoplasmic reticulum to Golgi vesicle-mediated transport grouped by SHC1P1-low versus SHC1P1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SHC1P1→partner) and Y-score (partner→SHC1P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADEndoplasmic reticulum to Golgi vesicle-mediated transport →+0.048+0.073<.001<.001312
STADrRNA modification →+0.041+0.077<.001<.001312
STADPositive regulation of intracellular transport →+0.049+0.073<.001<.001312
STADRegulation of generation of precursor metabolites and energy →+0.038+0.073<.001<.001312
STADRegulation of mRNA catabolic process →+0.039+0.079<.001<.001311
STADOrganelle disassembly →+0.052+0.073<.001<.001311
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,247 associations by consensus.

Endoplasmic reticulum to Golgi vesicle-mediated transport by SHC1P1 expression — STAD

Box plot of Endoplasmic reticulum to Golgi vesicle-mediated transport in SHC1P1-low vs SHC1P1-high samples in STAD.

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Exploration