SH3YL1

Across TCGA patient cohorts, SH3YL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,452 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SH3YL1-associated proteins across cancer lineages are AIF1_S39, THEMIS2, and THEMIS2_T593. Each is linked with SH3YL1 in more than 5 cancer types. Because this analysis shows association rather than direction, both SH3YL1-to-partner and partner-to-SH3YL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SH3YL1 versus AIF1_S39 in GBM, with a Pearson correlation of -0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SH3YL1→partner) and Y-score (partner→SH3YL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	AIF1_S39 →	-0.709	-0.332	<.001	<.001	3	6
UCEC	THEMIS2 →	-0.494	-0.391	<.001	<.001	3	5
CCRCC	THEMIS2_T593 →	-0.533	-0.592	<.001	<.001	3	5
UCEC	PLEKHO2_T311 →	-0.428	-0.516	<.001	<.001	3	5
GBM	CYTH4 →	-0.456	-0.311	<.001	<.001	3	5
GBM	MYO1F →	-0.555	-0.335	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,452 associations by consensus.

SH3YL1 vs AIF1_S39 — GBM

Explore this scatter interactively →