SH3YL1

Across TCGA patient cohorts, SH3YL1 mutation is significantly associated with the RNA expression of many other genes, with 1,988 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SH3YL1-associated genes across cancer lineages are RNU6-1169P, LGALS16, and RNU6-1107P. Each is linked with SH3YL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SH3YL1-to-partner and partner-to-SH3YL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1169P grouped by SH3YL1-low versus SH3YL1-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SH3YL1→partner) and Y-score (partner→SH3YL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	RNU6-1169P →	+0.445	+5.421	<.001	.005	3	2
READ	LGALS16 →	+0.090	+7.276	<.001	<.001	3	2
LUSC	RNU6-1107P →	+0.369	+4.984	<.001	.009	3	2
BLCA	PSAT1P4 →	+0.178	+5.038	<.001	.009	3	2
UCEC	RN7SKP230 →	+0.270	+1.699	.001	.008	3	2
UCEC	DYNLT3P2 →	+0.291	+1.825	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,988 associations by consensus.

RNU6-1169P by SH3YL1 expression — READ

Explore this box plot interactively →