SH3YL1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SH3YL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,995 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible SH3YL1-associated GO terms across cancer lineages are Carbohydrate biosynthetic process, Establishment of epithelial cell apical/basal polarity, and Sensory perception of salty taste. Each is linked with SH3YL1 in more than 11 cancer types. Because this analysis shows association rather than direction, both SH3YL1-to-partner and partner-to-SH3YL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Carbohydrate biosynthetic process grouped by SH3YL1-low versus SH3YL1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SH3YL1→partner) and Y-score (partner→SH3YL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
URINARY_TRACTCarbohydrate biosynthetic process →-0.078-2.155.007<.001312
STOMACHEstablishment of epithelial cell apical/basal polarity →-0.271-2.770<.001<.001311
OESOPHAGUSSensory perception of salty taste →+1.360+2.305<.001<.001311
OVARYPositive regulation of cyclase activity →-0.152-1.184<.001.006310
URINARY_TRACTKeratinocyte development →-0.542-2.783<.001<.001310
STOMACHCytotoxic T cell degranulation →+0.337+3.078<.001<.001310
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,995 associations by consensus.

Carbohydrate biosynthetic process by SH3YL1 expression — URINARY_TRACT

Box plot of Carbohydrate biosynthetic process in SH3YL1-low vs SH3YL1-high samples in URINARY_TRACT.

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Exploration