SH3TC2

Across TCGA patient cohorts, SH3TC2 RNA expression is significantly associated with the RNA expression of many other genes, with 16,803 significant associations in total. UVM shows the largest number of these associations.

The most reproducible SH3TC2-associated genes across cancer lineages are SH3TC2-DT, MFAP3, and TMC7. Each is linked with SH3TC2 in more than 28 cancer types. Because this analysis shows association rather than direction, both SH3TC2-to-partner and partner-to-SH3TC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SH3TC2 versus SH3TC2-DT in LAML, with a Pearson correlation of 0.92.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SH3TC2→partner) and Y-score (partner→SH3TC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	SH3TC2-DT →	+0.858	+1.223	<.001	<.001	3	29
THYM	MFAP3 →	+1.609	+0.110	<.001	.001	3	25
CHOL	TMC7 →	+1.495	+1.008	.003	<.001	2	25
UVM	CSNK1A1 →	+1.268	+0.642	<.001	<.001	3	24
CHOL	RASA1 →	+1.356	+1.004	.001	<.001	3	24
THYM	CAST →	+1.138	+0.090	<.001	<.001	3	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,803 associations by consensus.

SH3TC2 vs SH3TC2-DT — LAML

Explore this scatter interactively →