SH3RF3

Across TCGA patient cohorts, SH3RF3 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,409 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SH3RF3-associated proteins across cancer lineages are SEPTIN2, PRKG1, and SEPTIN11. Each is linked with SH3RF3 in more than 7 cancer types. Because this analysis shows association rather than direction, both SH3RF3-to-partner and partner-to-SH3RF3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SH3RF3 versus SEPTIN2 in PDAC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SH3RF3→partner) and Y-score (partner→SH3RF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	SEPTIN2 →	+0.311	+0.433	<.001	<.001	3	8
UCEC	PRKG1 →	+0.657	+0.580	<.001	.002	3	8
BRCA	SEPTIN11 →	+0.448	+0.663	<.001	<.001	3	7
PDAC	KANK2_S375 →	+0.595	+0.473	<.001	<.001	3	7
OV	ANTXR1 →	+0.733	+0.918	<.001	.001	3	7
HNSC	MAP1A →	+0.591	+0.636	<.001	.001	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,409 associations by consensus.

SH3RF3 vs SEPTIN2 — PDAC

Explore this scatter interactively →