SH3RF3

Across TCGA patient cohorts, SH3RF3 protein abundance is significantly associated with the RNA expression of many other genes, with 2,926 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SH3RF3-associated genes across cancer lineages are PRELID3B, ARMC1, and MRPL19. Each is linked with SH3RF3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SH3RF3-to-partner and partner-to-SH3RF3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SH3RF3 versus PRELID3B in BRCA, with a Pearson correlation of -0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SH3RF3→partner) and Y-score (partner→SH3RF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PRELID3B →	-0.820	-0.641	.006	.004	3	2
BRCA	ARMC1 →	-0.874	-0.663	<.001	<.001	3	2
BRCA	MRPL19 →	-0.685	-0.739	.003	.001	3	2
UCEC	CDK2 →	-0.476	-0.419	.001	.001	3	2
UCEC	YEATS4 →	-0.793	-0.444	.005	.002	3	2
BRCA	GRSF1 →	-0.477	-0.783	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,926 associations by consensus.

SH3RF3 vs PRELID3B — BRCA

Explore this scatter interactively →