SH3RF3

Across TCGA cell cohorts, SH3RF3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,879 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SH3RF3-associated GO terms across cancer lineages are Positive regulation of focal adhesion assembly, Positive regulation of cytoskeleton organization, and Establishment of epithelial cell apical/basal polarity. Each is linked with SH3RF3 in more than 11 cancer types. Because this analysis shows association rather than direction, both SH3RF3-to-partner and partner-to-SH3RF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of focal adhesion assembly grouped by SH3RF3-low versus SH3RF3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SH3RF3→partner) and Y-score (partner→SH3RF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of focal adhesion assembly →	+0.226	+1.886	<.001	<.001	3	12
BREAST	Positive regulation of cytoskeleton organization →	+0.063	+1.326	<.001	<.001	3	11
URINARY_TRACT	Establishment of epithelial cell apical/basal polarity →	+0.212	+1.390	<.001	<.001	3	10
BREAST	Positive regulation of supramolecular fiber organization →	+0.086	+1.359	<.001	<.001	3	10
BONE	Regulation of cell-substrate junction organization →	+0.133	+1.268	<.001	<.001	3	10
OESOPHAGUS	Regulation of atrial cardiac muscle cell membrane depolarization →	+1.355	+0.868	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,879 associations by consensus.

Positive regulation of focal adhesion assembly by SH3RF3 expression — BONE

Explore this box plot interactively →