SH3KBP1

Across TCGA patient cohorts, SH3KBP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,273 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SH3KBP1-associated proteins across cancer lineages are SH3KBP1_S587, RGS10, and SH3KBP1_S503. Each is linked with SH3KBP1 in more than 8 cancer types. Because this analysis shows association rather than direction, both SH3KBP1-to-partner and partner-to-SH3KBP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SH3KBP1 versus SH3KBP1_S587 in OV, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SH3KBP1→partner) and Y-score (partner→SH3KBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SH3KBP1_S587 →	+0.965	+0.715	.001	.001	3	9
CCRCC	RGS10 →	+0.435	+0.456	<.001	<.001	3	7
LSCC	SH3KBP1_S503 →	+0.782	+0.548	<.001	<.001	3	7
LSCC	SH3KBP1_S511 →	+0.701	+0.632	<.001	<.001	3	7
GBM	MICAL1 →	+0.412	+0.526	<.001	<.001	3	7
GBM	RCSD1 →	+0.628	+0.484	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,273 associations by consensus.

SH3KBP1 vs SH3KBP1_S587 — OV

Explore this scatter interactively →