SH3GLB2

Across TCGA patient cohorts, SH3GLB2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,878 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SH3GLB2-associated proteins across cancer lineages are RABGAP1, BSPRY, and NIBAN2. Each is linked with SH3GLB2 in more than 6 cancer types. Because this analysis shows association rather than direction, both SH3GLB2-to-partner and partner-to-SH3GLB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SH3GLB2 versus RABGAP1 in OV, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SH3GLB2→partner) and Y-score (partner→SH3GLB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RABGAP1 →	+0.364	+0.725	<.001	<.001	3	7
CCRCC	BSPRY →	+0.889	+0.395	<.001	<.001	3	7
OV	NIBAN2 →	+0.426	+0.837	<.001	<.001	3	6
OV	PDIA6 →	-0.519	-0.912	<.001	<.001	3	6
CCRCC	HSP90B1 →	-0.458	-0.427	<.001	<.001	3	6
OV	CALR →	-0.351	-0.514	.004	.008	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,878 associations by consensus.

SH3GLB2 vs RABGAP1 — OV

Explore this scatter interactively →