SH3GLB2

Across TCGA patient cohorts, SH3GLB2 protein abundance is significantly associated with the RNA expression of many other genes, with 12,193 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SH3GLB2-associated genes across cancer lineages are ARRDC1, CDCA3, and CENPO. Each is linked with SH3GLB2 in more than 5 cancer types. Because this analysis shows association rather than direction, both SH3GLB2-to-partner and partner-to-SH3GLB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SH3GLB2 versus ARRDC1 in BRCA, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SH3GLB2→partner) and Y-score (partner→SH3GLB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ARRDC1 →	+0.744	+0.284	<.001	<.001	3	6
BRCA	CDCA3 →	-0.945	-0.384	<.001	<.001	3	5
UCEC	CENPO →	-0.725	-0.371	<.001	<.001	3	5
LUAD	NUF2 →	-1.015	-0.165	<.001	.006	3	5
BRCA	EXO1 →	-0.898	-0.303	<.001	.001	3	5
BRCA	AURKB →	-1.108	-0.362	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,193 associations by consensus.

SH3GLB2 vs ARRDC1 — BRCA

Explore this scatter interactively →