SH3GL2

Across TCGA patient cohorts, SH3GL2 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,774 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SH3GL2-associated proteins across cancer lineages are PSIP1, PTBP2, and TMOD2. Each is linked with SH3GL2 in more than 3 cancer types. Because this analysis shows association rather than direction, both SH3GL2-to-partner and partner-to-SH3GL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SH3GL2 versus PSIP1 in OV, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SH3GL2→partner) and Y-score (partner→SH3GL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PSIP1 →	+0.508	+0.928	.003	.001	3	4
LSCC	PTBP2 →	+0.930	+0.684	<.001	.002	3	4
GBM	TMOD2 →	+0.410	+1.757	<.001	<.001	3	4
LSCC	KIF5C →	+0.570	+0.639	.001	.006	3	4
LSCC	MYEF2 →	+0.655	+0.461	<.001	<.001	3	3
HNSC	PGAM1_S31 →	-0.523	-0.478	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,774 associations by consensus.

SH3GL2 vs PSIP1 — OV

Explore this scatter interactively →