SH3GL2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SH3GL2 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SH3GL2-associated genes across cancer lineages are OR6C2. Each is linked with SH3GL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SH3GL2-to-partner and partner-to-SH3GL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR6C2 grouped by SH3GL2-low versus SH3GL2-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SH3GL2→partner) and Y-score (partner→SH3GL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINOR6C2 →+0.015+4.977<.001.00731
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

OR6C2 by SH3GL2 expression — SKIN

Box plot of OR6C2 in SH3GL2-low vs SH3GL2-high samples in SKIN.

Explore this box plot interactively →

Exploration