SH3BP5L

Across TCGA patient cohorts, SH3BP5L RNA expression is significantly associated with the protein abundance of many other proteins, with 11,282 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SH3BP5L-associated proteins across cancer lineages are GATAD2B, BROX, and RPRD2. Each is linked with SH3BP5L in more than 6 cancer types. Because this analysis shows association rather than direction, both SH3BP5L-to-partner and partner-to-SH3BP5L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SH3BP5L versus GATAD2B in LSCC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SH3BP5L→partner) and Y-score (partner→SH3BP5L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GATAD2B →	+0.307	+0.541	.002	<.001	3	7
LUAD	BROX →	+0.341	+0.401	<.001	<.001	3	6
GBM	RPRD2 →	+0.288	+0.314	<.001	.001	3	5
LSCC	CDC73 →	+0.208	+0.473	<.001	<.001	3	4
GBM	DDX17 →	+0.259	+0.283	.001	.004	3	4
GBM	UBN2 →	+0.422	+0.260	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,282 associations by consensus.

SH3BP5L vs GATAD2B — LSCC

Explore this scatter interactively →