SH3BP5

Across TCGA patient cohorts, SH3BP5 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,737 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SH3BP5-associated proteins across cancer lineages are CAVIN3, FES, and TLN1. Each is linked with SH3BP5 in more than 5 cancer types. Because this analysis shows association rather than direction, both SH3BP5-to-partner and partner-to-SH3BP5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SH3BP5 versus CAVIN3 in COAD, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SH3BP5→partner) and Y-score (partner→SH3BP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CAVIN3 →	+0.499	+0.541	<.001	<.001	3	6
GBM	FES →	+0.360	+0.494	<.001	<.001	3	6
PDAC	TLN1 →	+0.291	+0.476	.002	<.001	3	6
COAD	PPP1R12C →	+0.394	+0.575	<.001	<.001	3	6
PDAC	VIM_S73 →	+0.619	+0.413	<.001	<.001	3	6
LSCC	ARHGAP31_S954 →	+0.475	+0.360	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,737 associations by consensus.

SH3BP5 vs CAVIN3 — COAD

Explore this scatter interactively →