SH3BP5

Across TCGA patient cohorts, SH3BP5 protein abundance is significantly associated with the RNA expression of many other genes, with 7,224 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SH3BP5-associated genes across cancer lineages are DPT, JAM2, and EBF1. Each is linked with SH3BP5 in more than 3 cancer types. Because this analysis shows association rather than direction, both SH3BP5-to-partner and partner-to-SH3BP5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SH3BP5 versus DPT in BRCA, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SH3BP5→partner) and Y-score (partner→SH3BP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DPT →	+1.449	+0.448	<.001	<.001	3	4
BRCA	JAM2 →	+0.940	+0.416	<.001	<.001	3	4
BRCA	EBF1 →	+0.951	+0.496	<.001	<.001	3	4
BRCA	SH3BP5-AS1 →	+0.718	+0.427	<.001	.001	3	4
UCEC	CNRIP1 →	+0.857	+0.502	<.001	.001	3	4
BRCA	DDR2 →	+1.124	+0.429	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,224 associations by consensus.

SH3BP5 vs DPT — BRCA

Explore this scatter interactively →