SH3BP5

Across TCGA cell cohorts, SH3BP5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,936 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SH3BP5-associated GO terms across cancer lineages are Plasma membrane to endosome transport, Glucuronate catabolic process, and Regulation of Wnt protein secretion. Each is linked with SH3BP5 in more than 8 cancer types. Because this analysis shows association rather than direction, both SH3BP5-to-partner and partner-to-SH3BP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Plasma membrane to endosome transport grouped by SH3BP5-low versus SH3BP5-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SH3BP5→partner) and Y-score (partner→SH3BP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Plasma membrane to endosome transport →	+0.140	+1.995	<.001	.004	3	9
BONE	Glucuronate catabolic process →	-0.190	-1.563	<.001	<.001	3	7
SKIN	Regulation of Wnt protein secretion →	+0.096	+1.480	<.001	.001	3	7
UPPER_AERODIGESTIVE_TRACT	Negative regulation of transcription by RNA polymerase III →	+0.142	+1.279	<.001	.005	3	7
SKIN	Response to L-glutamate →	+0.149	+1.969	<.001	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	Molting cycle →	-0.165	-1.131	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,936 associations by consensus.

Plasma membrane to endosome transport by SH3BP5 expression — BONE

Explore this box plot interactively →