SH3BP4

Across TCGA patient cohorts, SH3BP4 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,389 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SH3BP4-associated proteins across cancer lineages are SH3BP4_S246, SH3BP4_S296, and SH3BP4_S19. Each is linked with SH3BP4 in more than 9 cancer types. Because this analysis shows association rather than direction, both SH3BP4-to-partner and partner-to-SH3BP4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SH3BP4 versus SH3BP4_S246 in BRCA, with a Pearson correlation of 0.72.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SH3BP4→partner) and Y-score (partner→SH3BP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SH3BP4_S246 →	+1.200	+1.241	<.001	<.001	3	10
UCEC	SH3BP4_S296 →	+0.768	+0.906	<.001	<.001	3	9
BRCA	SH3BP4_S19 →	+1.381	+1.026	<.001	<.001	3	8
BRCA	SH3BP4_S131 →	+0.535	+0.973	<.001	<.001	3	7
BRCA	ICAM1 →	-0.683	-0.966	<.001	<.001	3	7
GBM	ARHGAP45 →	-0.526	-0.522	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,389 associations by consensus.

SH3BP4 vs SH3BP4_S246 — BRCA

Explore this scatter interactively →