SH3BP2

Across TCGA patient cohorts, SH3BP2 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,824 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible SH3BP2-associated proteins across cancer lineages are SH3BP2_S416, SH3BP2_S444, and MLYCD. Each is linked with SH3BP2 in more than 4 cancer types. Because this analysis shows association rather than direction, both SH3BP2-to-partner and partner-to-SH3BP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SH3BP2 versus SH3BP2_S416 in GBM, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SH3BP2→partner) and Y-score (partner→SH3BP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SH3BP2_S416 →	+0.364	+0.334	<.001	<.001	3	5
LSCC	SH3BP2_S444 →	+0.720	+0.539	<.001	<.001	3	5
UCEC	MLYCD →	-0.293	-0.641	<.001	<.001	3	5
LSCC	CEBPB →	+0.330	+0.579	<.001	<.001	3	4
LSCC	GCA →	+0.537	+0.591	<.001	<.001	3	4
BRCA	MRPL41 →	-0.350	-0.386	.003	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,824 associations by consensus.

SH3BP2 vs SH3BP2_S416 — GBM

Explore this scatter interactively →