SH3BGRL2

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SH3BGRL2 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,916 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SH3BGRL2-associated proteins across cancer lineages are DDAH1, SPTAN1, and SPTBN1. Each is linked with SH3BGRL2 in more than 6 cancer types. Because this analysis shows association rather than direction, both SH3BGRL2-to-partner and partner-to-SH3BGRL2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SH3BGRL2→partner) and Y-score (partner→SH3BGRL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCDDAH1 →+0.612+0.995<.001<.00137
OVSPTAN1 →+0.344+0.915<.001<.00127
PDACSPTBN1 →+0.373+1.227<.001<.00136
HNSCTYMP →-0.662-1.162<.001<.00136
UCECTYMP_T154 →-0.974-0.947<.001<.00136
LUADCAPN5 →+0.584+0.889.002.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 20,916 associations by consensus.

Exploration