Across TCGA patient cohorts, SH3BGRL2 protein abundance is significantly associated with the RNA expression of many other genes, with 13,485 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SH3BGRL2-associated genes across cancer lineages are CGNL1, EMCN, and BDH2. Each is linked with SH3BGRL2 in more than 5 cancer types. Because this analysis shows association rather than direction, both SH3BGRL2-to-partner and partner-to-SH3BGRL2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SH3BGRL2→partner) and Y-score (partner→SH3BGRL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CGNL1 →	+0.871	+0.313	<.001	<.001	3	6
UCEC	EMCN →	+0.824	+0.284	<.001	.001	3	6
CCRCC	BDH2 →	+0.624	+0.350	.001	.003	3	6
BRCA	AQP7 →	+1.216	+0.621	<.001	<.001	3	6
LUAD	IYD →	+1.547	+0.471	<.001	<.001	3	6
LUAD	ECRG4 →	+0.735	+0.349	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,485 associations by consensus.

Exploration

SH3BGRL2 survival (RNA) · tumor vs normal (RNA) · all SH3BGRL2 data types