Across TCGA patient cohorts, SH3BGR protein abundance is significantly associated with the RNA expression of many other genes, with 261 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SH3BGR-associated genes across cancer lineages are RAB36, RHOU, and PRMT1. Each is linked with SH3BGR in more than 1 cancer types. Because this analysis shows association rather than direction, both SH3BGR-to-partner and partner-to-SH3BGR results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SH3BGR→partner) and Y-score (partner→SH3BGR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RAB36 →	+3.040	+0.204	.007	<.001	3	1
OV	RHOU →	+1.630	+0.519	.002	.007	3	1
OV	PRMT1 →	+0.714	+0.519	.004	.007	3	1
OV	SREK1IP1 →	+1.305	+0.519	<.001	.007	3	1
OV	CDC20B →	+6.880	+0.449	.007	.003	3	1
OV	TMEM67 →	+2.114	+0.449	.009	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 261 associations by consensus.

Exploration

SH3BGR survival (RNA) · tumor vs normal (RNA) · all SH3BGR data types