Across TCGA patient cohorts, SH2D7 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,136 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible SH2D7-associated GO terms across cancer lineages are Protein-containing complex disassembly, Protein acylation, and Heterochromatin organization. Each is linked with SH2D7 in more than 27 cancer types. Because this analysis shows association rather than direction, both SH2D7-to-partner and partner-to-SH2D7 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SH2D7→partner) and Y-score (partner→SH2D7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Protein-containing complex disassembly →	+0.081	+0.569	<.001	.001	2	28
STAD	Protein acylation →	+0.043	+0.223	<.001	<.001	3	27
ESCA	Heterochromatin organization →	+0.071	+0.312	<.001	<.001	2	27
UCS	DNA biosynthetic process →	+0.052	+0.433	<.001	<.001	3	26
UCS	Negative regulation of gene expression, epigenetic →	+0.059	+0.462	<.001	<.001	3	26
STAD	Epigenetic regulation of gene expression →	+0.063	+0.236	<.001	.002	2	27

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,136 associations by consensus.

Exploration

SH2D7 survival (RNA) · tumor vs normal (RNA) · all SH2D7 data types