Across TCGA cell cohorts, SH2D7 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,745 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SH2D7-associated GO terms across cancer lineages are Negative regulation of gene expression, epigenetic, Negative regulation of syncytium formation by plasma membrane fusion, and Negative regulation of myoblast fusion. Each is linked with SH2D7 in more than 12 cancer types. Because this analysis shows association rather than direction, both SH2D7-to-partner and partner-to-SH2D7 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SH2D7→partner) and Y-score (partner→SH2D7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Negative regulation of gene expression, epigenetic →	+0.062	+0.097	<.001	.002	3	13
BLOOD_Lymphoma	Negative regulation of syncytium formation by plasma membrane fusion →	+0.073	+0.057	<.001	.002	3	12
BLOOD_Lymphoma	Negative regulation of myoblast fusion →	+0.074	+0.057	<.001	.002	3	11
LUNG_NSCLC_LUSC	Mitotic cytokinesis →	+0.072	+0.136	.004	<.001	3	11
OVARY	Heterochromatin formation →	+0.063	+0.108	<.001	.001	3	11
OVARY	Heterochromatin organization →	+0.059	+0.104	<.001	.002	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,745 associations by consensus.

Exploration

SH2D7 survival (RNA) · tumor vs normal (RNA) · all SH2D7 data types