Across TCGA cell cohorts, SH2D5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,103 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SH2D5-associated GO terms across cancer lineages are Positive regulation of establishment of T cell polarity, Regulation of establishment of T cell polarity, and Pyrimidine nucleotide biosynthetic process. Each is linked with SH2D5 in more than 13 cancer types. Because this analysis shows association rather than direction, both SH2D5-to-partner and partner-to-SH2D5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SH2D5→partner) and Y-score (partner→SH2D5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Positive regulation of establishment of T cell polarity →	+0.238	+1.866	<.001	<.001	3	14
STOMACH	Regulation of establishment of T cell polarity →	+0.263	+1.580	<.001	.001	3	11
PANCREAS	Pyrimidine nucleotide biosynthetic process →	+0.095	+1.577	<.001	<.001	3	10
LIVER	Skeletal myofibril assembly →	+0.333	+1.690	.006	.007	2	10
LUNG_NSCLC_LUSC	Positive regulation of focal adhesion assembly →	+0.196	+2.051	<.001	<.001	3	9
SOFT_TISSUE	Replication-born double-strand break repair via sister chromatid exchange →	-0.077	-0.852	<.001	.006	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,103 associations by consensus.

Exploration

SH2D5 survival (RNA) · tumor vs normal (RNA) · all SH2D5 data types