Across TCGA cell cohorts, SH2D1B RNA expression is significantly associated with the go_rna of many other GO terms, with 1,826 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible SH2D1B-associated GO terms across cancer lineages are Regulation of alpha-beta T cell activation, Apoptotic signaling pathway, and Negative regulation of metallopeptidase activity. Each is linked with SH2D1B in more than 6 cancer types. Because this analysis shows association rather than direction, both SH2D1B-to-partner and partner-to-SH2D1B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SH2D1B→partner) and Y-score (partner→SH2D1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Regulation of alpha-beta T cell activation →	+0.073	+0.948	<.001	<.001	3	7
BREAST	Apoptotic signaling pathway →	+0.045	+0.107	.001	.008	3	7
PANCREAS	Negative regulation of metallopeptidase activity →	+0.176	+0.741	.003	.002	3	7
PANCREAS	Regulation of cellular component size →	+0.072	+0.986	<.001	.002	3	7
OESOPHAGUS	Membrane biogenesis →	+0.087	+0.092	.002	.007	2	7
PANCREAS	Positive regulation of alpha-beta T cell activation →	+0.087	+0.768	<.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,826 associations by consensus.

Exploration

SH2D1B survival (RNA) · tumor vs normal (RNA) · all SH2D1B data types