Across TCGA cell cohorts, SH2D1A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,334 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SH2D1A-associated GO terms across cancer lineages are Glucose catabolic process, Protein polyubiquitination, and Negative regulation of gene expression, epigenetic. Each is linked with SH2D1A in more than 6 cancer types. Because this analysis shows association rather than direction, both SH2D1A-to-partner and partner-to-SH2D1A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SH2D1A→partner) and Y-score (partner→SH2D1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Glucose catabolic process →	+0.080	+0.029	<.001	.001	3	7
LARGE_INTESTINE	Protein polyubiquitination →	+0.030	+0.082	<.001	.004	3	6
PANCREAS	Negative regulation of gene expression, epigenetic →	+0.035	+0.035	.008	.005	3	6
BLOOD_Leukemia	Regulation of autophagosome maturation →	+0.035	+2.465	.006	<.001	3	6
BONE	Regulation of myoblast fusion →	+0.079	+0.257	.002	<.001	3	5
BONE	Pre-mRNA catabolic process →	+0.136	+0.191	.008	.006	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,334 associations by consensus.

Exploration

SH2D1A survival (RNA) · tumor vs normal (RNA) · all SH2D1A data types