SGTA

Across TCGA patient cohorts, SGTA RNA expression is significantly associated with the protein abundance of many other proteins, with 15,253 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SGTA-associated proteins across cancer lineages are THOP1, UHRF1, and CHAF1A_S141. Each is linked with SGTA in more than 6 cancer types. Because this analysis shows association rather than direction, both SGTA-to-partner and partner-to-SGTA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SGTA versus THOP1 in OV, with a Pearson correlation of 0.60.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SGTA→partner) and Y-score (partner→SGTA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	THOP1 →	+0.356	+0.473	<.001	<.001	3	7
UCEC	UHRF1 →	+0.542	+0.468	<.001	<.001	3	6
LSCC	CHAF1A_S141 →	+0.806	+0.501	<.001	<.001	3	6
GBM	CHAF1B →	+0.643	+0.350	<.001	<.001	3	6
GBM	DNMT1 →	+0.342	+0.216	<.001	<.001	3	6
LSCC	KHSRP →	+0.317	+0.472	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,253 associations by consensus.

SGTA vs THOP1 — OV

Explore this scatter interactively →