SGSM3

Across TCGA patient cohorts, SGSM3 protein abundance is significantly associated with the RNA expression of many other genes, with 17,515 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SGSM3-associated genes across cancer lineages are AGR3, BCAS1, and AGR2. Each is linked with SGSM3 in more than 7 cancer types. Because this analysis shows association rather than direction, both SGSM3-to-partner and partner-to-SGSM3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SGSM3 versus AGR3 in BRCA, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SGSM3→partner) and Y-score (partner→SGSM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	AGR3 →	+3.089	+0.421	<.001	<.001	3	8
LUAD	BCAS1 →	+1.683	+0.364	<.001	<.001	3	8
BRCA	AGR2 →	+3.140	+0.485	<.001	<.001	3	7
BRCA	MLPH →	+2.747	+0.503	<.001	<.001	3	7
BRCA	TFF1 →	+3.637	+0.359	<.001	<.001	3	7
HNSC	ZG16B →	+2.582	+0.345	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,515 associations by consensus.

SGSM3 vs AGR3 — BRCA

Explore this scatter interactively →