SGSM3

Across TCGA cell cohorts, SGSM3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,959 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SGSM3-associated GO terms across cancer lineages are Symbiont-mediated disruption of host cellular anatomical structure, Symbiont-mediated disruption of host anatomical structure, and Positive regulation of intracellular estrogen receptor signaling pathway. Each is linked with SGSM3 in more than 13 cancer types. Because this analysis shows association rather than direction, both SGSM3-to-partner and partner-to-SGSM3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Symbiont-mediated disruption of host cellular anatomical structure grouped by SGSM3-low versus SGSM3-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SGSM3→partner) and Y-score (partner→SGSM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Symbiont-mediated disruption of host cellular anatomical structure →	+0.143	+1.139	<.001	.001	3	14
UPPER_AERODIGESTIVE_TRACT	Symbiont-mediated disruption of host anatomical structure →	+0.143	+1.139	<.001	.001	3	14
LARGE_INTESTINE	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.177	+1.158	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.121	-1.124	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Flagellated sperm motility →	-0.124	-0.987	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.121	-1.124	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,959 associations by consensus.

Symbiont-mediated disruption of host cellular anatomical structure by SGSM3 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →