SGSM1

Across TCGA pan-cancer cohorts, SGSM1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SGSM1 data layer compared with 26 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher SGSM1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SGSM1 expression acts as an unfavorable survival marker.

LSCC, LUAD, and PDAC are the cancer types where SGSM1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Median	All	0.490	1.000	.003	10	view →
LUAD	OS	Quartile	All	0.549	1.000	.027	6	view →
PDAC	DFS	Median	All	0.194	0.415	.040	4	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

SGSM1–LSCC (DFS)

Open the LSCC breakdown →