SGSM1

Across TCGA patient cohorts, SGSM1 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,796 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SGSM1-associated proteins across cancer lineages are HECTD1, PPP1R9A_S840, and BRMS1L. Each is linked with SGSM1 in more than 4 cancer types. Because this analysis shows association rather than direction, both SGSM1-to-partner and partner-to-SGSM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SGSM1 versus HECTD1 in HNSC, with a Pearson correlation of -0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SGSM1→partner) and Y-score (partner→SGSM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	HECTD1 →	-0.415	-0.603	<.001	<.001	3	5
HNSC	PPP1R9A_S840 →	+1.931	+0.800	<.001	<.001	3	5
UCEC	BRMS1L →	+0.336	+0.804	<.001	<.001	3	5
CCRCC	CENPV →	+0.568	+0.744	.001	<.001	3	5
CCRCC	DYNLL2 →	+0.308	+0.946	<.001	<.001	3	5
CCRCC	GFPT2 →	-0.840	-0.756	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,796 associations by consensus.

SGSM1 vs HECTD1 — HNSC

Explore this scatter interactively →