SGPP2

Across TCGA patient cohorts, SGPP2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,567 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SGPP2-associated proteins across cancer lineages are SPAST, SFN, and HOOK2. Each is linked with SGPP2 in more than 4 cancer types. Because this analysis shows association rather than direction, both SGPP2-to-partner and partner-to-SGPP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SGPP2 versus SPAST in LSCC, with a Pearson correlation of 0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SGPP2→partner) and Y-score (partner→SGPP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SPAST →	+0.382	+0.882	<.001	<.001	3	5
UCEC	SFN →	+0.724	+0.713	.002	<.001	3	4
UCEC	HOOK2 →	+0.219	+0.467	<.001	<.001	3	4
GBM	MARK2 →	+0.203	+0.569	<.001	<.001	3	4
UCEC	ARHGEF5 →	+0.342	+0.740	<.001	<.001	3	4
LUAD	LAD1 →	+0.523	+0.857	.006	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,567 associations by consensus.

SGPP2 vs SPAST — LSCC

Explore this scatter interactively →