SGPP2

Across TCGA patient cohorts, SGPP2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,697 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SGPP2-associated genes across cancer lineages are CRISPLD2, MREG, and ADRA2A. Each is linked with SGPP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SGPP2-to-partner and partner-to-SGPP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SGPP2 versus CRISPLD2 in OV, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SGPP2→partner) and Y-score (partner→SGPP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CRISPLD2 →	-1.543	-1.084	.006	.007	3	2
OV	MREG →	+0.876	+1.070	<.001	.005	3	2
OV	ADRA2A →	-1.712	-1.326	.001	.001	3	2
OV	CD248 →	-1.503	-1.058	.007	.004	3	2
OV	FBLN1 →	-1.523	-0.821	.007	.009	3	2
CCRCC	WIPF3 →	+1.369	+1.733	.007	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,697 associations by consensus.

SGPP2 vs CRISPLD2 — OV

Explore this scatter interactively →