SGPP2

Across TCGA cell cohorts, SGPP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,598 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SGPP2-associated GO terms across cancer lineages are Collagen fibril organization, Positive regulation of transcription by RNA polymerase I, and Regulation of transcription of nucleolar large rRNA by RNA polymerase I. Each is linked with SGPP2 in more than 9 cancer types. Because this analysis shows association rather than direction, both SGPP2-to-partner and partner-to-SGPP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Collagen fibril organization grouped by SGPP2-low versus SGPP2-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SGPP2→partner) and Y-score (partner→SGPP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Collagen fibril organization →	-0.336	-1.891	.002	.003	2	10
BLOOD_Lymphoma	Positive regulation of transcription by RNA polymerase I →	+0.109	+1.429	<.001	<.001	3	9
BONE	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.172	+0.658	<.001	<.001	3	8
SOFT_TISSUE	Regulation of transcription by RNA polymerase I →	+0.106	+0.636	<.001	<.001	3	8
BONE	Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.159	+0.765	<.001	<.001	3	8
LUNG_SCLC	Regulation of myoblast fusion →	+0.098	+1.823	.001	.004	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,598 associations by consensus.

Collagen fibril organization by SGPP2 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →