SGPP1

Across TCGA patient cohorts, SGPP1 protein abundance is significantly associated with the protein abundance of many other proteins, with 23,268 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SGPP1-associated proteins across cancer lineages are SGPP1_S112, TMX1, and CKAP4_S26. Each is linked with SGPP1 in more than 9 cancer types. Because this analysis shows association rather than direction, both SGPP1-to-partner and partner-to-SGPP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SGPP1 versus SGPP1_S112 in BRCA, with a Pearson correlation of 0.69.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SGPP1→partner) and Y-score (partner→SGPP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SGPP1_S112 →	+0.957	+0.911	<.001	<.001	3	10
UCEC	TMX1 →	+0.707	+0.905	<.001	<.001	3	8
BRCA	CKAP4_S26 →	+0.849	+0.546	<.001	<.001	3	7
BRCA	SLC39A7 →	+0.965	+0.875	<.001	<.001	3	7
PDAC	SLC66A2_S110 →	+0.820	+0.449	<.001	<.001	3	7
BRCA	SYVN1 →	+0.557	+0.739	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,268 associations by consensus.

SGPP1 vs SGPP1_S112 — BRCA

Explore this scatter interactively →