SGPP1

Across TCGA cell cohorts, SGPP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,425 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SGPP1-associated GO terms across cancer lineages are ER to Golgi ceramide transport, Regulation of hippo signaling, and Regulation of protein binding. Each is linked with SGPP1 in more than 12 cancer types. Because this analysis shows association rather than direction, both SGPP1-to-partner and partner-to-SGPP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ER to Golgi ceramide transport grouped by SGPP1-low versus SGPP1-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SGPP1→partner) and Y-score (partner→SGPP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ER to Golgi ceramide transport →	+0.157	+1.384	<.001	<.001	3	13
SKIN	Regulation of hippo signaling →	+0.062	+0.446	<.001	.008	3	12
OESOPHAGUS	Regulation of protein binding →	+0.090	+1.526	.002	<.001	3	11
CNS	Regulation of keratinocyte differentiation →	+0.090	+0.660	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Protein catabolic process at synapse →	+0.137	+1.137	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Protein catabolic process at postsynapse →	+0.137	+1.137	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,425 associations by consensus.

ER to Golgi ceramide transport by SGPP1 expression — BLOOD_Leukemia

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