SGO2

Across TCGA cell cohorts, SGO2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,560 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SGO2-associated GO terms across cancer lineages are Regulation of nuclear division, Negative regulation of nuclear division, and Centromeric sister chromatid cohesion. Each is linked with SGO2 in more than 19 cancer types. Because this analysis shows association rather than direction, both SGO2-to-partner and partner-to-SGO2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of nuclear division grouped by SGO2-low versus SGO2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SGO2→partner) and Y-score (partner→SGO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of nuclear division →	+0.133	+1.380	.005	.001	3	20
OESOPHAGUS	Negative regulation of nuclear division →	+0.162	+1.698	.003	<.001	3	20
BLOOD_Myeloma	Centromeric sister chromatid cohesion →	+0.179	+1.273	<.001	<.001	3	20
UPPER_AERODIGESTIVE_TRACT	Regulation of G2/M transition of mitotic cell cycle →	+0.090	+1.044	<.001	<.001	3	19
BREAST	Negative regulation of cell cycle process →	+0.074	+1.128	<.001	<.001	3	19
OESOPHAGUS	Regulation of mitotic sister chromatid separation →	+0.168	+1.149	.001	.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,560 associations by consensus.

Regulation of nuclear division by SGO2 expression — OESOPHAGUS

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